One problem related to brake master cylinder has been reported for the 2006 Lexus Rx400h. The most recently reported issues are listed below.
After the vehicle been working perfectly, after overnight the various warning lamps, including the mal function indicator lamp, slip indicator light, brake system warning light, master warning light, and check vsc system message showed up on the instrument panel. When the vehicle were in motion, the breaks went in blank, continuing running even with the break pedal pressed. The vehicle only stoped with the emergency breaks. After get the vehicle checked at my nearest Lexus dealer, the service advisor indicate than the issue has been caused by the actuator and the break master cylinder, which would cost $4,595 plus tax.