general problems of the 2010 Mercedes Benz E350

17 problems related to equipment have been reported for the 2010 Mercedes Benz E350. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2010 Mercedes Benz E350 based on all problems reported for the 2010 E350.

1 Equipment problem

Failure Date: 11/18/2025

While driving once I start braking once the car is around 3mph it shifts from drive into park and abruptly comes to a stop. Sometimes I am able to put it back into drive sometimes I have to turn the car off and reinsert the key just to get it back into drive. Normally happens after an hour or so of driving the when I try to come to a complete stop the car will automatically shift into park. This is very dangerous as it can ruin the transmission also the person driving behind me can run into the back of my car. Is there any recall for this issue.

2 Equipment problem

Failure Date: 08/06/2024

August 2024, while driving on a 4 lane highway at 65 mph, a warning appeared on gauge cluster saying that electronic stability control and traction control inoperable. This caused the car to reduce power, requiring me to quickly pull over. The car continued running but I was limited on mph and gear selection (aka limp mode). I turned the car off, allowing the systems to reset. After driving approximately 1 miles, the same warnings appeared. Fortunately, I was within a mile from home at the time so I was able to "limp" the car home. The next day, I checked the car again by driving in my neighborhood with the result. I had the car transported on roll back to express oil and tire in barboursville, wv as my "local" mb dealer is an hour away. They checked the car and the engine control module was defective and needed replacement. The cost of the service including new mb parts and programming would be $2,495. I tried for 2 months to secure funding to fix the car to no avail. I had the car towed on roll back again but back to my house. The car has sat since then.

3 Equipment problem

Failure Date: 07/10/2023

Rear suspension control arm bracket rusted, broken off from frame of vehicle makes a slight to moderate sound when driving or going off bumps I avoid rough surfaces, I drive at a respectable speed ,I never came across as long I owed this vehicle.

4 Equipment problem

Failure Date: 05/13/2023

Per the technician: "the rear subframe is rusted out and the lateral strut arm is starting to break away". Because of this issue, the car unknowingly presented a safety risk to occupants and other drivers. A failure of the subframe or connected components could have resulted in a serious accident. Photos are attached. The vehicle is currently available for inspection upon request. There were no warning indicators to this issue. The issue was found only because the car was being serviced for brake pads. Mercedes benz USA customer care said there was no recall or other warranty covering the issue and said the vehicle was outside their "good will assistance program". The vehicle is no longer able to be driven.

5 Equipment problem

Failure Date: 03/18/2023

Steering wheel lock mechanism failed.

6 Equipment problem

Failure Date: 01/21/2023

Rear sub-frame rusting/rotting.

7 Equipment problem

Failure Date: 10/21/2022

Rear subframe rusted through making the vehicle unsafe to drive. I was told to park it until I had it fixed. The subframe had begun flexing as I drove and make a loud noise.

8 Equipment problem

Failure Date: 07/05/2019

Mercedes benz knows that their car door paneling has a defective problem and will fall off. They are ignoring my concern and refuse to pay for it. I last week I called 800-367-6372 and spoke with a live mb representative via the phone regarding case number: 2-2940129122. Today, 12/30/2019, customer advocate manager, darrell with no last name called me from phone 800-367-6372 ext 4632 and advised that he could not assist. Executive referral manager: service manager case number: 2-2940129122 phone: 800-367-6372 ext 4632 I am very concerned as both of the doors on my coupe are having the trim to come off of the car. This is a known defect with the car door panel clips. Darrel admitted that he is aware of the issue, but lacked the authority do anything about the issue. I realize that the car is no longer under warranty, but this is horrible. I have seen two other cars at my dealership with the same trouble and getting their panels repaired. I spoke with the rbm of alpharetta manager, craig and the service representative tobias and they advised that the repair would be around $1,020 per door. (each door has two pieces of trim - 207-720-22-22-2a02 for the larger trim at the cost of $350. 45 and the same for the labor. Then the smaller piece of trim under part number 207-720-20-22-64-2a04 at the cost of $135. 15 an d the labor would be an additional $135. 15. So the passender door would cost $971. 20 plus tax or $1039. 18 for each door. For the total repair for the trim on both doors equaling $2,078. 36. We have purchased and currently own and maintained two Mercedes Benz. On 12/30/2019 I received a call from the Mercedes Benz customer advovate representative darrell (no last name) and he advised that he is aware of other cars with this same trouble. Darrell advised that he can be reached at phone 800-367-6372 extension: 4632.

9 Equipment problem

Failure Date: 12/13/2018

Takata recall. Vehicle gear shifter broke when putting vehicle in drive from reverse, while making a broken u-turn (car in motion), on a city street.

10 Equipment problem

Failure Date: 06/21/2018

While driving on road at about 40 miles , it went into park after some jurking motion around June 13 2018 around 1 pm . We thought it was nothing serious, but again it happened on June 21 2018 at about 6 30 pm on city road with speed limit of 40 miles ,,, called Mercedes Benz dealer to report the issue and made the appointment, . . They could not find the problem or duplicate the issue for more than a week. I gave them ali the information I received from internet (see attachment), and finally they are telling me the issue is with electronic switch module , which will cost about $ 1500 plus tax . To us it is a serious safety issue and should have been reported earlier by other drivers too , and should be fixed with out charge. 4 pm to 7 pm coming from work is always a heavy traffic issue , it could have been worse , had it been hit by other vehicles.

11 Equipment problem

Failure Date: 01/26/2018

I was driving my 2010 mercedes E350 sedan at highway speeds, when out of nowhere the sunroof just shatters into pieces. There was no large object that came towards me. I had my screen pulled over, so thankfully most of the glass didn't come in the car. I pulled over to see what happened and called the toll road authority. They summoned an officer to help me. The officer searched the area of the freeway for any object that could have caused this, and found nothing. At closer inspection he and I noticed that glass bowed outward and no major body damage behind the sunroof indicated that no object caused this. I then went to the dealership and told them about this spontaneous shattering only to be told that it's impossible for something like this to happen on its own. I was told perhaps it's a 'pebble' and they would give me a quote to fix this with them. I am convinced that this shattered. . . In fact exploded (that's how it sounded) by itself and was a defective glass. Please look into this as I am relieved I didn't have my toddler in the back seat with the sunroof screen open for more light, only for it to have shattered and been all over him because of the wind direction!.

12 Equipment problem

Failure Date: 07/16/2017

Sporadically the car goes into park while the vehicle is in motion. This happens with a sudden jerk and is dangerous to the occupant and also to other vehicles as it comes to a sudden halt in the middle of the road. This is definitely a safety issue and can even be fatal/or cause serious injuries to the occupants of the vehicle and to the occupants of other vehicles. At other times it will keep shifting to park when the driver puts it into reverse or drive when stationary. Took it to the dealership and they say their diagnostics does not show a problem. When we called mercedes they say that if the dealer cannot see the problem there is no problem. We have finally been able to make a video recording but unfortunately the file is too large to attach due to the potential dangerous outcome we request that the higher level mercedes engineers look into and in the meantime the vehicle should be recalled.

13 Equipment problem

Failure Date: 09/01/2016

We brought this vehicle from 3rd party. Transmission gear sound is coming so hard. I have very low mileage only 48k. I wen to delar, he told me to change the transmission or contact head office to resolve this issue. I need someone to help me for next step.

14 Equipment problem

Failure Date: 12/03/2015

I bought a 2010 E350 mb in November of 2015 as a birthday gift. My 3rd week of own it the check engine light came on and keeps going on and off. Brought it back to the dealer where I bought it and told me to bring it to mb. Turn out to be heck engine light due to faulty camshaft adjuster solenoid on mercedes-benz E350. Why is their no recall on this, it cost $8,000. 00 to get it fixed?.

15 Equipment problem

Failure Date: 06/01/2015

The rearview camera on this vehicle operates intermittently. When it is not operating, the infotainment screen is completely black (no distortion, no flickering, no image at all. ) I realize that my vehicle is out of warranty (2010my,) but the issue began in 2015 and has been gradually getting more frequent. Numerous customers have been complaining about this concern on the forums from as early as 2013 (only 2-3 years into ownership as 2010 was the first model year of the w212 e-class generation. ) example forums: https://mbworld. Org/forums/e-class-w212/497565-no-camera-image-reverse-2. Html https://mbworld. Org/forums/e-class-w212/532189-reverse-cam-interimittently-not-working. Html https://mbworld. Org/forums/e-class-w212/706425-backup-camera-not-available. Html.

16 Equipment problem

Failure Date: 02/12/2015

The stitch seam of the "mb texture" of the driver's seat spontaneously burst upon my entering and sitting in the vehicle. The driver's door lock freezes and has not been operable via the key remote since then.

17 Equipment problem

Failure Date: 06/16/2010

We leased mercedes E350 year 2010 in February. Cars response was very good and we liked the car very much. On June 16 I drove the car on freeway for about 23 miles then on the road for another mile with couple of red light stops. Then I turned left into the parking lot and right turn in to the parking spot. As I was about to park I heard engine revving up , (this sound I never heard before even when I started the car) car lunged forward on the parking median with grass (incline). To avoid running into the car on the other side I turned right, I started pumping the break, there was a tree and car clipped bark of the tree, damaging front and side of the car. Car stopped crossing over to the right. Ignition key thing popped. Both air bags on the driver side were deployed, car stopped with two flat tires on the driver side. Luckily there was no on-coming car in the parking lot. It is my observation that some error had occurred for engine to rev up like this. Knee air bag did lot of damage to my legs. Left leg was bruised very heavily and swelled up where knee was not even visible. This is not to complain but to document the incidence. I want to make sure it does not happen again to me or anyone else.


Other Equipment related problems of the 2010 Mercedes Benz E350


E350 Service Bulletins
E350 Safety Recalls
E350 Defect Investigations