Mercedes Benz E350 owners have reported 117 power train related problems since 1996. Table 1 shows the 18 most common power train problems. The number one most common problem is related to the vehicle's power train (81 problems). The second most common problem is related to the vehicle's automatic transmission (7 problems). For details of each of the problem category, use the links in the table.
While driving a 2008 mercedes-benz E350 on 5/21/2025 around 1:50pm, the transmission suddenly failed while I was traveling at approximately 75 mph was on highway 76. As a result of the failure, the driver's side airbag deployed unexpectedly. Read details...
The contact owns a 2007 mercedes-benz E350. The contact stated while driving approximately 65 mph, the check engine warning light illuminated and with an abnormal sound coming from the gear shifter. The contact stated there was a failure with the transmission and the vehicle would not exceed 65 mph. Read details...
When I try to put the vehicle in park the car is stuck in drive or reverse. If the car is in reverse or if the vehicle is in drive and you use the gear selector to put the vehicle in park or change and gear the vehicle does not change the gear. Read details...
Tl-the contact owns a 2006 Mercedes Benz E350. The contact stated that while driving 45 mph and depressing the accelerator pedal, the vehicle would not respond. The contact had to shift gears from drive to park and back to drive before the vehicle would respond. Read details...
The contact owns a 2006 mercedes-benz E350. The contact stated that while traveling various speeds, the contact heard a grinding noise as the transmission slipped. The vehicle was taken to the dealer where it was found that the balance shaft needed to be replaced. The vehicle was not repaired. Read details...