One problem related to ignition has been reported for the 2003 Mercedes Benz E Class. The most recently reported issues are listed below.
Throttle control failure causing exactly a 20 second delay before the car would actually accelerate after pressing the accelerator. This caused me to be in nearly 3 accidents, because the car did not move when I was in the middle of an intersection and pulling out of a parking spot, cars were coming, but I could not move forward, until after the 20 second acceleration delay. When I turned the car into parkplace mercedes, the invoice showed that they had to replace my ignition system as well as the throttle control system.