Two problems related to software have been reported for the 2003 Mercedes Benz E Class. The most recently reported issues are listed below.
Electrical systems malfunctions. Service dept advised me that mercedes is aware of the issues (plural) but they have yet to reach a 'fix'. I have had my e500 for 7 months. I am suspecting that the fix may be impractical as was the case with the navigation software that could not be integrated - forcing mercedes to buy back their cars. I believe we are all getting false promises from mercedes-benz on any proposed fixes with the electrical bugs too.
The 2003 Mercedes Benz e500 has a faulty gateway module and software. This module has resulted in problems being reported in my car that the brakes, self restraint system, telephone system, and tire pressure have failed. I have no way of knowing if the the safty systems are operational or not. At this point I am driving a car that says my srs system is not working. I have been in the mercedes shop no less than 3 times to have the problem repaired. It simply re-occurs after each repair.