One problem related to noises during shifting has been reported for the 2006 Nissan Quest. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2006 Nissan Quest based on all problems reported for the 2006 Quest.
I have to replace the transmission in my 2006 Nissan Quest 3. 5 se minivan. The transmission has air-flow problems, hard shift, acceleration problems, and gear shifting problems. While driving in the city, the transmission will hard-shift while decelerating and parking. While accelerating the transmission will automatically shift to a higher gear (making a racing sound/like rapidly accelerating) then jump (making a hard jolting knocking noise - especially while accelerating to highway speeds around 50-55-60mph). During driving, the transmission makes a sound similar to a railroad locomotive that has gotten louder over the past few weeks. Also, there has been an issue of slow acceleration while approaching 20mph. Beyond 20mph the acceleration is fine. This issue was temporary but worrying because there was a distinct smell of something overheating coming not from the engine itself, but from the underside of the vehicle. I turned off the engine and let it cool down for about 2 hours, after which the acceleration issue disappeared, but I fear it will return. I took it to a mechanic during which he plugged in the diagnostic computer. It diagnosed 10 codes - all transmission related. I am forced to replace the transmission at a cost of approximately $2,500.