One problem related to transmission failure has been reported for the 2007 Nissan Titan. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2007 Nissan Titan based on all problems reported for the 2007 Titan.
I drove my Nissan out of the driveway, it started slipping, grinding. The transmission fluid check light would not come on at all, ever since I had it. Turns out transmission fluid tank empty. I was on major highway, could go 40 miles an hour, jerked out of gear with traffic behind me. Had tow it to transmission shop and transmission burned out. Faulty transmission light failed to warn me of problems. Nissan owners manual does not instruct you to check transmission fluid. It directs you to dealership. Had no warning light to alert me. Could have gotten killed.