One problem related to engine has been reported for the 2008 Toyota Camry. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2008 Toyota Camry based on all problems reported for the 2008 Camry.
I was driving along a rural road and my engine seized up and the car died. It turns out that the oil filter fell off at some point- 2 months after an oil change. The oil light did not come on until approximately 30 seconds before the car died. When the mechanic spoke with Toyota, he asked if this had occurred other times and was told they had heard of it happening once or twice. Since the engine had to be rebuilt, this is a rather costly problem to have occur. Fortunately I was in a relatively safe place to pull over and call for a tow truck.