One problem related to hatchback/liftgate has been reported for the 2000 Toyota Sienna. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2000 Toyota Sienna based on all problems reported for the 2000 Sienna.
My van had 66,000 miles on it and one day I opened the back hatch, which is rarely used, and the hatch handle broke-off in my hand. I have never had a back hatch handle break on any of my vans. I took and to dealer and it quite a while for them to repair it because of how the handle is position in rear door.