One problem related to transmission failure has been reported for the 2006 Chrysler 300C. The most recently reported issues are listed below.
The contact owns a 2006 Chrysler 300c. The contact stated that after starting the vehicle, the transmission failed to switch from the park position. The vehicle was towed to an independent mechanic where it was diagnosed that the transmission shift gear interlock lever failed and needed to be replaced. The vehicle was repaired. The manufacturer was notified of the failure. The failure mileage was 109,000.