One problem related to headlights turn off while driving has been reported for the 2005 Chrysler Pacifica. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2005 Chrysler Pacifica based on all problems reported for the 2005 Pacifica.
While driving home, late evening, I reached to turn on windshield washer and when I did that, the headlights went out, radio and a/c went dead, taillights went out. The only electrical components still working were dashlights, doorlocks, turn signals, and security system. Engine and power steering still worked. Fortunately, there was not much traffic, or it could have been a dangerous situation. I managed to pull into a parking lot and parked to assess things, but found I could not shift out of park because of interlock. Car was towed to mechanic, who diagnosed power distribution module failure - replaced the box, but it still has the same symptoms. So far, 12 days in the shop, with no solution in sight. I think such a general system failure does present a safety issue.