One problem related to equipment has been reported for the 2022 Ford E-450. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2022 Ford E-450 based on all problems reported for the 2022 E-450.
The tire pressure monitoring system fails frequently while being driven. The first few times I pulled off the road and checked the pressures, and they were normal. I had the system checked at a Ford dealership and they couldn't find any problem. It failed again. I returned to the dealership and they said they couldn't find a problem and there is nothing they could do for me. So I drive away from the dealership and the same thing happens. Believing that they can't do anything I keep driving and manually checking pressures. Problem returns. I went to a different Ford dealership and they said they found a faulty sensor and replaced it. The same problem came back after less than a few miles. I needed gas so I filled up and realized that after turning the ignition off and restarting, the light on the dash and the warning went away. I returned to that dealership and they said after hearing my explanation. They couldn't do anything unless the fault was active at the time I brought it to them. So I was told to drive it until I got the safety warning and to not shut it off until I got to a Ford dealership. Really!!! not all Ford dealerships will service the e450s with rvs built on the chassis. Reasonable? no way! there is a problem with the system that Ford should be able to correct. I don't feel safe having to pull over and check tire pressures on a busy highway. And it's not necessary if they address the problem and fix it.