One problem related to engine noise has been reported for the 2001 Ford F-250. The most recently reported issues are listed below.
I was in my Ford f250 v10 triton sitting idle at a red light when I heard a loud pop under my hood which was followed by a steam engine sound when I accelerated. Had it towed to a mechanic and found that my factory spark plug had blown out of the head. The mechanic told me this happens often with Ford triton motors. The mechanic used a helicoil type tooling to retap the hold and fit a collar in it that would accept a new spark plug. The cost was about $300 but the fact that this happens so often for this particular manufacturer seems to me that they should bare the cost for each occurrence.