One problem related to radiator has been reported for the 2009 Ford F-250. The most recently reported issues are listed below.
Leaking radiator hoses causing loss of coolant from engine. Leak is a hazard to environment and wildlife that may come in contace with ethylene glycol. Dealer indicates a design issue exists with radiator hose o-rings and Ford has redesigned the hoses to use double o-rings vs. The current single o-ring.