One problem related to ball joint has been reported for the 2000 Ford F-350. The most recently reported issues are listed below.
Blue smoke coming from tail pipe. Form letter reply. The tail latch was sticking, the rotor had to be machined, the windshield had to be re-sealed due to it leaking, the ball joints and serpentine belt were replaced, the valve cover gasket was leaking and had to be replaced.