One problem related to engine turbo-charger has been reported for the 2008 Ford F-350. The most recently reported issues are listed below.
The contact owns a 2008 Ford F-350 sd. While driving approximately 60 mph, the engine power decreased significantly. The contact was able to continue in operation with the poor turbo performance. The vehicle was taken to an authorized dealer for diagnosis. The technician stated that the turbocharger compressor shaft completely fractured and both thermostats had broken. The vehicle was not repaired. The failure mileage was approximately 94,442.