One problem related to diesel engine has been reported for the 2016 Ford F-350. The most recently reported issues are listed below.
When the 6. 7 diesel engine goes in to regeneration for the emission system the engine sometimes shudders and shakes violently. The valves rattle and there is a sudden loss of power and truck slows. Seems to be mostly when the truck is in a slight pull up a grade. But, it has done it on flat ground. This condition is very dangerous and wide spread throughout the Ford 6. 7 diesel engines. The dealer stated it was common with these 6. 7 diesel engines and a fix was coming but it has been over 2 years and no fix in site. My truck is a 2016 with only 10,000 miles. Ford knows there is a problem and won't fix it. The truck is at woody anderson Ford in huntsville, alabama in their truck shop. Their truck shop service manager told me of the problem when I reported what the truck was doing. Ford actually has a TSB for for customers who have reported this issue, but they have no desire to correct the programming. It is bad and something needs to be done before someone get hurt.