One problem related to frame and members has been reported for the 2006 Honda Odyssey. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2006 Honda Odyssey based on all problems reported for the 2006 Odyssey.
I brought my 2006 Honda Odyssey into the dealer for a brake master cylinder recall. Unbeknown to me I was informed that 2 motor mounts also needed to be replaced at the cost of $1350. The service manager explained to me that this is a common issue with the Odyssey and not part of regular maintenance. An online search reveals that many other owners of this van are experiencing the same situation. I thought Honda was known for safety but it appears it has also earned the reputation for defective motor mounts. At what point will Honda be held accountable for an obvious design flaw that jeopardizes the safety of its riders? my van has less than 60,000 miles and is just over the 5 year mark, so it is not covered under the warranty. As long as Honda is allowed to defer the cost of this repair to its owners it will. Hopefully it won't take someone to be seriously injured or killed before the appropriate action is taken. Its pretty obvious a recall is long overdue.