One problem related to manual transmission has been reported for the 2006 Honda Odyssey. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2006 Honda Odyssey based on all problems reported for the 2006 Odyssey.
New, 2006 Honda Odyssey, purchased new driven for 7 weeks. Leaking noticed on garage floor. Service department said there was a crack in the transmission casing that occurred during manufacturing process, that the mold it was made from must have been defective. Unfortunately, Honda refuses to replace the transmission with a new one, but will use a mish-mash of parts from 2005 & 2006 and claim it as refurbished. They will not guarantee that the parts did not come from vehicles damaged in hurricanes. Our new vehicle will now be a substandard vehicle. I think other vehicles that have transmission made from this lot should be investigated for the same factory defect, and that unsuspecting consumers not have to be forced to underwrite Honda's failed factory inspection process.