Three problems related to vehicle shudder have been reported for the 2010 Honda Odyssey. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2010 Honda Odyssey based on all problems reported for the 2010 Odyssey.
Vehicle vibrating while accelerating, replaced tires, brakes and checked everything else, but it is still vibrating specifically when accelerating.
Van has a significant shake (or "judder", shudder, vibration, or shimmy) when accelerating between 50 and 75 mph. Entire vehicle shakes, similar to one or more tires being out of balance but much worse. Judder goes away completely and instantly when I take my foot off the accelerator. During this period I had three all-wheel alignments and several tire balancings, but nothing work. It was only recently when I noticed it only occurred while accelerating and so it wasn't a tire or alignment problem.
At 7000 miles, the transmission made a very loud grinding and rattling noise, shaking the vehicle, when shifting from r to d. This was repeated at 25,000 miles several months after the software upgrade. In July of 2010, vehicle was brought in for memory steering, they replaced the right strut. November of 2010, the vehicle steering is unstable at low speeds when turning left. The sensation is either over-activity of the power steering pump or under-activity. Vehicle seems very unstable under low speed driving conditions, especially on bumpy roads. Vehicle taken to dealer, they could not identify anything abnormal.