One problem related to transmission slip out of gear has been reported for the 2006 Nissan Frontier. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2006 Nissan Frontier based on all problems reported for the 2006 Frontier.
The vehicle has 86,700 miles, I always took care of it, changing oil at 3000 mile intervals, never towed with it, etc. , etc. , while driving the trans slipped out of gear, luckily I was able to pull over and nobody was in back of me, when I got it to the dealer, they said the timing chain and guides needed replacement plus the radiator leaked and the trans cooler contaminated the transmission and they both had to be replaced and it cost me near $5000. 00 for total repairs.