One problem related to axle shaft seal has been reported for the 2001 Toyota Sequoia. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2001 Toyota Sequoia based on all problems reported for the 2001 Sequoia.
"oil leak from rear axle seal. Both side axle shaft assemblies were removed and replaced. The mechanic replaced the rear pads and turned the rear rotors due to grease build up on surfaces from the axle seal leak.