One problem related to transmission noise has been reported for the 2001 Toyota Sequoia. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2001 Toyota Sequoia based on all problems reported for the 2001 Sequoia.
One complaint is the transmission failed started making a grinding noise then failed to move any more had to replace transmission at my cost with no help offered by the dealer. And failed at 90,000 miles. Never noticed anything leading to this regular maintenance done.