One problem related to engine has been reported for the 2001 Chevrolet Silverado 2500. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2001 Chevrolet Silverado 2500 based on all problems reported for the 2001 Silverado 2500.
Engine quit without warning while towing 12,000 lb trailer forcing me to the side of the road. After a few minutes I was able to restart the engine and continue. Failed again shortly thereafter. I was eventually able to get home. Scan tool revealed crankshaft position sensor problem. I replaced the crankshaft position sensor myself.