One problem related to engine grinding noise has been reported for the 2001 Ford E-250. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2001 Ford E-250 based on all problems reported for the 2001 E-250.
No knowledge of anything wrong. A grinding noise started, took it to the Ford dealership that day, now we need a new transmission. This van has only 70,000 miles on it. This should not have happened.