One problem related to air conditioner has been reported for the 2016 Ford F-150. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2016 Ford F-150 based on all problems reported for the 2016 F-150.
I have a 2016 f150 with issues similar to NHTSA complaint id# 10127407. The problems are not intermittent, the part has failed & is not available from Ford at this time. The air conditioning quits completely & you cannot run the fan at all. You cannot roll down any windows in the vehicle & the vehicle gets well over 90 degrees inside while driving. This is a huge safety issue because when this doesn't work it also disables the airbags of the vehicle, cross traffic alert as well as tire pressure monitor failure along with other safety features. The seats no longer retract or move forward when the vehicle is started/shutoff. The key fob intermittently will not lock the doors of the vehicle & the alert on the truck says key not found. With the warm temperatures and no way to roll down the windows or turn on the ac or a blower fan makes this vehicle extremely unsafe to operate.