One problem related to engine rattling and whining sounds has been reported for the 2003 Ford F-250. The most recently reported issues are listed below.
While driving at 60 mph vehicle shut down. Vehicle will not start right up again. One hour into driving the problem started. Engine made a whistling sound. Other then that there were no warnings. Consumer has taken the vehicle in for the same problem a total of four times. Power steering and brakes shut down as a result of loss of engine power.