One problem related to driveshaft has been reported for the 2005 Ford F-250. The most recently reported issues are listed below.
The contact stated there was severe vibration when using the cruise control. He took the vehicle to the dealer, they reprogrammed a chip, and put three shims in driveshaft. Also, there was severe vibration in the acceleration of the vehicle. There has been vibration with the vehicle since purchasing it. The vehicle has been to the dealer many times, but they stated it was normal. The vehicle vibration is more severe in lower gears than at higher gears. The vehicle did this from the point of acceleration, there was no for warning.