One problem related to engine funny noise has been reported for the 2005 Ford F-250. The most recently reported issues are listed below.
The contact owns a 2005 Ford F-250. The contact was driving approximately 55 mph when there was a slight loss in engine power with an unusual noise. The failure became more severe over a period of time and occurred whenever the vehicle was in operation. The vehicle was taken to an authorized dealer who detected coolant seepage which caused substantial damage to the engine. The vehicle was repaired. The manufacturer was notified of the problem. The approximate failure mileage was 100,000.