One problem related to spare tire has been reported for the 2006 Ford F-250. The most recently reported issues are listed below.
I have bf goodrich rugged trail t/a 275 70 r18 tires on my 2006 Ford f250 which were purchased 25 months ago and have 22000 miles on them. While towing my travel trailer I experienced a slight vibration while driving. I immediately pulled over and checked the vehicle and camper for NY visible signs of a problem. Everything a appeared to be in good working order so I continued on driving slower. After about 10 miles the tire completely blew up damaging my vehicle and sending the tread of the tire across the other lanes traffic which almost caused a major vehicular accident. I thought it was bad luck. I changed the tire and continued down the road. After approximately another 200 miles I started getting the same vibration from the rear drivers side tire. Fearing another blow out and having no spare tire I pulled over and spent the night in a campground. The next morning I went out to get tires and upon the tire personal inspecting the tire they said that it had a air bubble under the tread and that it too would have more than likely blown out on me. I didn't think that this was coincidence anymore. So upon getting home I called bf goodrich and made a complaint. Then I researched the tires and saw that a bunch of them were recalled. Just that mine was not within the the manufacture's date code with in a few weeks. I feel that if I hadn't had that camper behind me that I probably could have lost control of my truck with possible catastrophic consequences.