One problem related to transmission gear slipping has been reported for the 2001 GMC Sierra. The most recently reported issues are listed below.
Transmission surges at all speeds. Intermittent. Deal states could not reproduce problem. Transmission has slipped into gear while taking off from a stoplight. Rpm's went up to 2000 before engaging gear.
| Automatic Transmission problems | |
| Transfer Case problems | |
| Driveshaft problems | |
| Axle Hubs problems | |
| Transmission Gear Slipping problems | |
| Differential Unit problems | |
| Noises During Shifting problems |