One problem related to coolant leaking has been reported for the 2006 Nissan Frontier. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2006 Nissan Frontier based on all problems reported for the 2006 Frontier.
Transmission is binding due to coolant leaking into transmission. Fluid is bubbled and looks like poached egg causing overheating. Transmission color is not correct, same problem as under investigation.