Toyota Tacoma owners have reported 2 problems related to power door locks not working (under the electrical system category). The most recently reported issues are listed below. Also please check out the statistics and reliability analysis of Toyota Tacoma based on all problems reported for the Tacoma.
I've had 5 door lock actuators fail on my 4 door Tacoma. Both passenger side locks were inoperative at the same time. When the door locks fail, the electronic locks and keyless entry do not work. The passenger-side doors do not have a key-hole backup, meaning that its not possible to unlock those doors without having to crawl through the vehicle from the driver's side. If I needed to get a child out of the back-seat quickly, that would not have been possible.
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I have had 8 electric door locks fail in the last three years.