One problem related to differential unit has been reported for the 2005 Ford F-150. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2005 Ford F-150 based on all problems reported for the 2005 F-150.
Limited slip rear differential clutch pack has needed to be replaced three times in 25,000 miles. Failure of components causes harsh vibration and control problems in turns and curves.