One problem related to transmission failure has been reported for the 2005 Ford F-150. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2005 Ford F-150 based on all problems reported for the 2005 F-150.
Vehicle's transmission failed after only 18 months, 38,925 miles. Dealer unable to determine why transmission failed. No lack of fluid, vehicle is not used to tow. Could only state that excessive heat build up in transmission and resulted in failure. Vehicle and been driven home prior evening with no issues, next morning failed at start up. Manufacturer will not warranty due to mileage, replaced with a rebuilt unit at a cost of $2,800.