One problem related to rearview mirror has been reported for the 2010 Ford F-150. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2010 Ford F-150 based on all problems reported for the 2010 F-150.
Warmed up car before church. Turned on front and rear defroster. Backed up, put it in drive and heard what sounded like something crashing into my roof or a gunshot. I stopped and inspected the steel body parts and could find nothing. Driving down the road I noticed in my rearview mirror that my right side of my sliding rear window had shattered. It remained in place. I took this into the dealer on Monday and they fixed it saying a reed switch had malfunctioned allowing the glass to get too hot and shattering.