One problem related to battery dead has been reported for the 2000 Ford F-250. The most recently reported issues are listed below.
Since 2006 and before, I have had unexplained incidences of battery failures and dashboard warnings. The windshield was replaced in 2006 at my request. My battery was replaced in 2006. I also had a temporary engine shutdown about this time. I had battery replacement in 2009 and 2012. On 11/02/2012 I attempted to start my f250 only to discover about a pint of water in the floor tray. I jump started, continued the trip only to discover the heater fan still operating! after further checks, my Ford dealer provided a TSB 04-23-9 which had no warning of the potential electronic malfunctions or damages and not mailed to me. I had the defect corrected by a local shop and Ford was mailed my complaint on 11/28/2012 and have received no answer. I have had more than enough mailing for service and Ford should have been required to inform me.