One problem related to instrument panel has been reported for the 2000 Ford F-250. The most recently reported issues are listed below.
The contact owns a 2000 Ford f250. While driving approximately 50 mph, the instrument panel cluster stopped functioning. The contact nearly crashed, but was able to maneuver off the roadway. He drove to a dealer, but they could not assist. The contact had to purchase a new panel from the dealer. The current and failure mileages were 89,000.