One problem related to transmission noise has been reported for the 1999 Ford F-350. The most recently reported issues are listed below.
A rattling noise can be heard coming from the automatic transmission. The fluids were changed but the noise can still be heard. Also, there is a tire complaint. The left front tire disintegrated while driving 50 mph. Per results performed; there were metal(s) underlined were elevated excessive wear. The left front tire blew out and caused the vehicle to go hard to the left, and a few weeks later, the vehicle begun to jump and separated like the first tire incident. A whine/grinding noise would also be displayed when the vehicle was driven below 35 mph.