One problem related to engine shut off without warning has been reported for the 2010 Ford F-250. The most recently reported issues are listed below.
Driving on expressway in georgia vehicle shut down approximately 90 miles after getting gas. Towed vehicle to Ford dealer who said there was gas in the diesel fuel tank which resulted in blown engine. State farm was called, after about 2 weeks they took samples and claimed there was no evidence of gas. They claimed there were issues with the engine (6. 4 super duty Ford) in the past. We put 20,000 into the truck to have the engine replaced. Now we are wondering if this could happen again.