One problem related to differential unit has been reported for the 2000 Toyota Sienna. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2000 Toyota Sienna based on all problems reported for the 2000 Sienna.
The differential/transmission on my 2000 Toyota Sienna is failing. It was diagnosed at under 100,000 miles. I am the original owner and have completed all required service.