GMC Yukon owners have reported 2 problems related to power door locks not working (under the electrical system category). The most recently reported issues are listed below. Also please check out the statistics and reliability analysis of GMC Yukon based on all problems reported for the Yukon.
Door lock failure, driver and rear passenger.
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all problems of the 2008 GMC Yukon
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Two door locks quit working, then would lock and unlock while driving.