One problem related to transmission not engage has been reported for the 2005 Honda Odyssey. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2005 Honda Odyssey based on all problems reported for the 2005 Odyssey.
This behavior happened a few times in the past according to my wife. The last time happened on 1/30/09 while I was driving on a city street under normal speed and suddenly the transmission lost power, the d drive failed to engage. I immediately move the gear shift several time to re-engage the d gear. Very unsafe, unpredictable and scare in a busy street.