399 problems have been reported for the 2007 Mercedes Benz E350. The following chart shows the 20 most common problems for 2007 Mercedes Benz E350. The number one most common problem is related to the vehicle's fuel system, other with 211 problems. The second most common problem is related to the vehicle's fuel system, gasoline (41 problems).
The following chart shows the number of problems reported during each of the service years since the debut of the 2007 Mercedes Benz E350 in 2007.
| Service Year | Number of Problems |
|---|---|
| 2026 | |
| 2025 | |
| 2024 | |
| 2023 | |
| 2022 | |
| 2021 | |
| 2020 | |
| 2019 | |
| 2018 | |
| 2017 | |
| 2016 | |
| 2015 | |
| 2014 | |
| 2013 | |
| 2012 | |
| 2011 | |
| 2010 | |
| 2009 | |
| 2008 | |
| 2007 |
When making the decision between buying a new or used Mercedes Benz E350, the following table can be used to compare the 2007 Mercedes Benz E350 with the Mercedes Benz E350 from other model years. Note that the number of problems reported for the 2007 E350 is 399 while the average number of problems reported for the 19 model years of the Mercedes Benz E350 is 138.